Article
Novel analytical methods applied to type 1 diabetes genome-scan data.
American journal of human genetics - 1 Apr 2004
Pociot Flemming, Karlsen Allan E, Pedersen Claus B, Aalund Mogens, Nerup Jørn
Abstract excerpt
Complex traits like type 1 diabetes mellitus (T1DM) are generally taken to be under the influence of multiple genes interacting with each other to confer disease susceptibility and/or protection. Although novel methods are being developed, analyses of whole-genome scans are most often performed with multipoint methods that work under the assumption that multiple trait loci are unrelated to each other; that is,...
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