Article
Applications of machine learning and data mining methods to detect associations of rare and common variants with complex traits.
Genetic epidemiology - 1 Sept 2014
Lu Ake Tzu-Hui, Austin Erin, Bonner Ashley, Huang Hsin-Hsiung, Cantor Rita M
Abstract excerpt
Machine learning methods (MLMs), designed to develop models using high-dimensional predictors, have been used to analyze genome-wide genetic and genomic data to predict risks for complex traits. We summarize the results from six contributions to our Genetic Analysis Workshop 18 working group; these investigators applied MLMs and data mining to analyses of rare and common genetic variants measured in pedigrees. To...
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