Article
Prepulse facilitation and prepulse inhibition in schizophrenia patients and their unaffected siblings.
Biological psychiatry - 1 Mar 2004
Wynn Jonathan K, Dawson Michael E, Schell Anne M, McGee Mark, Salveson Dustin, Green Michael F
Abstract excerpt
BACKGROUND: Deficits in schizophrenia patients and their first-degree relatives have been reported in prepulse inhibition (PPI), a phenomenon that measures an early stage of information processing (sensorimotor gating). It is less clear whether these information processing deficits extend to prepulse facilitation (PPF), which measures a later stage of generalized alerting or orienting. METHODS: This study...
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