Article
Immune regulation and graft survival in kidney transplant recipients are both enhanced by human leukocyte antigen matching.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Apr 2004
Rodriguez Daniel S, Jankowska-Gan Ewa, Haynes Lynn D, Leverson Glenn, Munoz Alejandro, Heisey Dennis, Sollinger Hans W, Burlingham William J
Abstract excerpt
We hypothesized that donor/recipient sharing of the human leukocyte antigen (HLA) involved in allopeptide presentation to the T regulatory cell increases the incidence of immune regulation, thus contributing to long-term graft survival. Peripheral blood mononuclear cells (PBMC) were obtained from 40 living related donor (LRD) and 31 cadaver renal transplant recipients. The trans vivo delayed type hypersensitivity...
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