Article
Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy.
Journal of the American Society of Nephrology : JASN - 1 Jul 2004
Poggio Emilio D, Clemente Michael, Riley Jocelyn, Roddy Meagan, Greenspan Neil S, Dejelo Cora, Najafian Nader, Sayegh Mohamed H, Hricik Donald E, Heeger Peter S
Abstract excerpt
The pathogenesis of chronic allograft nephropathy (CAN) involves both immunologic (antigen-dependent) and nonimmunologic (antigen-independent) mechanisms. In order to provide further insight into the immunologic basis of this disease, a cross-sectional analysis of cellular and humoral immunity in human renal allograft recipients with or without deteriorating renal function and biopsy proven CAN was performed....
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