Article
Characterization of the calcium-binding sites of Listeria monocytogenes InlB.
Biochemical and biophysical research communications - 2 Apr 2004
Marino Michael, Banerjee Manidipa, Copp Jeremy, Dramsi Shaynoor, Chapman Tara, van der Geer Peter, Cossart Pascale, Ghosh Partho
Abstract excerpt
The Listeria monocytogenes protein InlB promotes invasion of mammalian cells through activation of the receptor tyrosine kinase Met. The InlB N-cap, a approximately 40 residue part of the domain that binds Met, was previously observed to bind two calcium ions in a novel and unusually exposed manner. Because subsequent work raised questions about the existence of these calcium-binding sites, we assayed calcium...
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