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Article

Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro.

Journal of virology - 1 Apr 2004

Gradi Alessandra, Foeger Nicole, Strong Rebecca, Svitkin Yuri V, Sonenberg Nahum, Skern Tim, Belsham Graham J

Abstract excerpt

Foot-and-mouth disease virus (FMDV) induces a very rapid inhibition of host cell protein synthesis within infected cells. This is accompanied by the cleavage of the eukaryotic translation initiation factor 4GI (eIF4GI). The cleavage of the related protein eIF4GII has now been analyzed. Within FMDV-infected cells, cleavage of eIF4GI and eIF4GII occurs with similar kinetics. Cleavage of eIF4GII is induced in cells...

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Identifiers

PMID: 15016848
DOI: 10.1128/jvi.78.7.3271-3278.2004
PMCID: PMC371048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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