Article
Characterization of the G91del CRYBA1/3-crystallin protein: a cause of human inherited cataract.
Human molecular genetics - 1 May 2004
Reddy M A, Bateman O A, Chakarova C, Ferris J, Berry V, Lomas E, Sarra R, Smith M A, Moore A T, Bhattacharya S S, Slingsby C
Abstract excerpt
Congenital cataract is a leading cause of visual disability in children. Inherited isolated (non-syndromic) cataract represents a significant proportion of cases and the identification of genes responsible for inherited cataract will lead to a better understanding of the mechanism of cataract formation at the molecular level both in congenital and age-related cataract. Crystallins are abundantly expressed in the...
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