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Article

Beta-2-microglobulin haplotypes in U.S. beef cattle and association with failure of passive transfer in newborn calves.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2004

Clawson Michael L, Heaton Michael P, Chitko-McKown Carol G, Fox James M, Smith Timothy P L, Snelling Warren M, Keele John W, Laegreid William W

Abstract excerpt

Failure of passive transfer (FPT) is a condition in which neonates do not acquire protective serum levels of maternal antibodies. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FCGRT) and beta-2-microglobulin ( B2M). Previously, two FCGRT haplotypes were associated with differences in immunoglobulin G (IgG)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15014972
DOI: 10.1007/s00335-003-2320-x

Genes

FCGRT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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