Article
Association of FcRn Heavy Chain Encoding Gene (FCGRT) Polymorphisms with IgG Content in Bovine Colostrum.
Animal biotechnology - 1 Jan 2009
Zhang Ran, Zhao Zhihui, Zhao Yaofeng, Kacskovics Imre, Eijk Marjolein van der, Groot Nanda de, Li Ning, Hammarstrom Lennart
Abstract excerpt
In this study, we evaluated haplotypes of the bovine FCGRT (encoding the FcRn heavy chain) and their relationship to the IgG concentration in bovine colostrum. Four single nucleotide polymorphism (SNP), classified into five haplotypes, were identified in a total of 49 Holstein-Frisians cows. Haplotype 5 was found to be significantly associated with a high IgG level ([OR] = 9.90, 95%CI = 1.11-88.34, p = 0.016) and...
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