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Article

Probing essential residues for cellular uptake with a cationic nuclear localization signal sequence.

The journal of peptide research : official journal of the American Peptide Society - 1 Feb 2004

Ragin A D, Chmielewski J

Abstract excerpt

The nuclear localization signal sequence (NLS) of the transcription factor NF-kappaB is a cationic peptide with the ability to cross the cytoplasmic membrane and facilitate the delivery of attached cargo, such as DNA and proteins, to cells. Previous research had pointed to the essential role of cationic residues, therefore, the importance of residues within the NLS of NF-kappaB was evaluated for cellular uptake...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15009537
DOI: 10.1111/j.1399-3011.2003.00115.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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