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Article

Monozygotic twins with tuberous sclerosis discordant for the severity of developmental deficits.

Neurology - 9 Mar 2004

Humphrey Ayla, Higgins J Nicholas P, Yates John R W, Bolton Patrick F

Abstract excerpt

A pair of monozygotic male twins with tuberous sclerosis (TS) were followed between 18 months and 3 years of age. Twin A with 25 large cortical tubers and hence extensive brain involvement was moderately mentally retarded and met criteria for autism. The other twin had more (n = 31) but smaller tubers. He was not mentally retarded and did not meet criteria for autism. This study provides evidence that nongenetic...

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Source

Identifiers

PMID: 15007135
DOI: 10.1212/01.wnl.0000113745.58425.ef

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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