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Article

Risk factors for the development of autism spectrum disorder in children with tuberous sclerosis complex: protocol for a systematic review.

Systematic reviews - 8 Mar 2017

Mitchell Rebecca, Barton Sarah, Harvey A Simon, Williams Katrina

Abstract excerpt

BACKGROUND: Tuberous sclerosis complex (TSC) is an autosomal dominant condition, caused by mutations in either the TSC1 or TSC2 gene. It has widespread systemic manifestations and is associated with significant neurological morbidity. In addition to seizures and cerebral pathology including cortical tubers, subependymal nodules, subependymal giant cell astrocytoma and abnormal white matter, there are recognised...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28270230
DOI: 10.1186/s13643-017-0448-0
PMCID: PMC5341363

Genes

TSC1
TSC2

Provenance

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