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Article

Cortical dysplasia and autistic trait severity in children with Tuberous Sclerosis Complex: a clinical epidemiological study.

European child & adolescent psychiatry - 1 Jun 2018

Mous Sabine E, Overwater Iris E, Vidal Gato Rita, Duvekot Jorieke, Ten Hoopen Leontine W, Lequin Maarten H, de Wit Marie-Claire Y, Dieleman Gwendolyn C

Abstract excerpt

Tuberous Sclerosis Complex (TSC) is characterized by a high prevalence of autism spectrum disorders (ASD). Little is known about the relation between cortical dysplasia and ASD severity in TSC. We assessed ASD severity (using the Autism Diagnostic Observation Scale), tuber and radial migration line (RML) count and location, and cognitive functioning in 52 children with TSC and performed regression and mediation...

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Identifiers

PMID: 29063203
DOI: 10.1007/s00787-017-1066-z
PMCID: PMC5973967

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