Article
The first green lineage cdc25 dual-specificity phosphatase.
Cell cycle (Georgetown, Tex.) - 1 Apr 2004
Khadaroo B, Robbens S, Ferraz C, Derelle E, Eychenié S, Cooke R, Peaucellier G, Delseny M, Demaille J, Van de Peer Y, Picard A, Moreau H
Abstract excerpt
The Cdc25 protein phosphatase is a key enzyme involved in the regulation of the G(2)/M transition in metazoans and yeast. However, no Cdc25 ortholog has so far been identified in plants, although functional studies have shown that an activating dephosphorylation of the CDK-cyclin complex regulates the G(2)/M transition. In this paper, the first green lineage Cdc25 ortholog is described in the unicellular alga...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Western
- Cell Cycle
- Cell Cycle Proteins
- Cell Lineage
- Cloning, Molecular
- Dose-Response Relationship, Drug
- G2 Phase
- Glutathione Transferase
- Mitosis