Article
The contribution of factor V Leiden and prothrombin G20210A mutation to the risk of central venous catheter-related thrombosis.
Haematologica - 1 Feb 2004
Van Rooden Cornelis J, Rosendaal Frits R, Meinders A Edo, Van Oostayen Jacques A, Van Der Meer Felix J M, Huisman Menno V
Abstract excerpt
BACKGROUND AND OBJECTIVES: The purpose of this study was to assess the incidence of central venous catheter (CVC)-related thrombosis and the contribution of two common inherited coagulation disorders (factor V Leiden, prothrombin G20210A mutation) to this complication in a large hospital population. DESIGN AND METHODS: In a prospective setting, patients were assessed daily for signs and symptoms suggestive of...
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