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Article

Factor V Leiden mutation does not account for central venous catheter-related thrombosis.

American journal of hematology - 1 Jun 1998

Riordan M, Weiden P L

Abstract excerpt

Indwelling central venous access devices are frequently associated with catheter-related thrombosis. The factor V Leiden gene mutation decreases the sensitivity of factor V to the anticoagulant activity of activated protein C, and has been shown to be the most common inherited defect associated with a hypercoagulable state. In this study, we sought to determine whether an increased prevalence of the factor V gene...

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PMID: 9625586
DOI: 10.1002/(sici)1096-8652(199806)58:2<150::aid-ajh13>3.0.co;2-f

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Source receipt: pubmed, retrieved 7 Sept 2026.

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