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Article

The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes.

The Journal of clinical endocrinology and metabolism - 1 Mar 2004

Hamaguchi Kazuyuki, Terao Hideo, Kusuda Yoichiro, Yamashita Tsutomu, Hazoury Bahles J A, Cruz LL Modesto, Brugal V Luis Iván, Jongchong W Bienvenido, Yoshimatsu Hironobu, Sakata Toshiie

Abstract excerpt

The human glycoprotein PC-1 codon Q121 allele has been correlated with insulin resistance, but not with type 2 diabetes or obesity. We investigated the prevalence of PC-1 Q121 in the Dominican Republic population (755 subjects studied) and whether this variant is associated with insulin resistance, obesity, or type 2 diabetes. The prevalence of PC-1 Q121 was high compared with that in other populations. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15001634
DOI: 10.1210/jc.2003-031387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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