Article
Reinvestigation of the requirement of cytosolic ATP for mitochondrial protein import.
The Journal of biological chemistry - 7 May 2004
Asai Takeyoshi, Takahashi Takashi, Esaki Masatoshi, Nishikawa Shuh-ichi, Ohtsuka Kenzo, Nakai Masato, Endo Toshiya
Abstract excerpt
Protein import into mitochondria requires the energy of ATP hydrolysis inside and/or outside mitochondria. Although the role of ATP in the mitochondrial matrix in mitochondrial protein import has been extensively studied, the role of ATP outside mitochondria (external ATP) remains only poorly characterized. Here we developed a protocol for depletion of external ATP without significantly reducing the import...
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