Article
Mycobacterium tuberculosis/HIV-1 coinfection and disease: role of human leukocyte antigen variation.
The Journal of infectious diseases - 15 Mar 2004
Louie Leslie G, Hartogensis Wendy E, Jackman Rachael P, Schultz Kathleen A, Zijenah Lynn S, Yiu Carina H-Y, Nguyen Viet D, Sohsman Marie Y, Katzenstein David K, Mason Peter R
Abstract excerpt
Genetic variation influences immune responses and may contribute to differential development of tuberculosis (TB), particularly in immunosuppressed individuals. To examine the risk of Mycobacterium tuberculosis infection progressing to disease in the context of M. tuberculosis/human immunodeficiency virus (HIV) type 1 coinfection, HIV-1 RNA load and human leukocyte antigen (HLA) genotypes were determined among...
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