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Article

Disruption of spermatogenesis in mice lacking A-type lamins.

Journal of cell science - 1 Mar 2004

Alsheimer Manfred, Liebe Bodo, Sewell Lori, Stewart Colin L, Scherthan Harry, Benavente Ricardo

Abstract excerpt

Nuclear lamins are structural protein components of the nuclear envelope. Mutations in LMNA, the gene coding for A-type lamins, result in several human hereditary diseases, the laminopathies, which include Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy, familial partial lipodystrophy and Hutchinson-Gilford progeria. Similar to the human conditions, it has been shown that Lmna(-/-) mice develop severe...

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Source

Identifiers

PMID: 14996939
DOI: 10.1242/jcs.00975

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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