Article
Error and repair catastrophes: A two-dimensional phase diagram in the quasispecies model.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Jan 2004
Tannenbaum Emmanuel, Shakhnovich Eugene I
Abstract excerpt
This paper develops a two-gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair. The first gene, denoted by sigma(via), yields a viable organism with first-order growth rate constant k>1 if it is equal to some target "master" sequence sigma(via,0). The second gene, denoted by sigma(rep), yields an organism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.