Article
Error threshold in RNA quasispecies models with complementation.
Journal of theoretical biology - 7 Aug 2010
Sardanyés Josep, Elena Santiago F
Abstract excerpt
A general assumption of quasispecies models of replicons dynamics is that the fitness of a genotype is entirely determined by its sequence. However, a more biologically plausible situation is that fitness depends on the proteins that catalyze metabolic reactions, including replication. In a stirred population of replicons, such as viruses replicating and accumulating within the same cell, the association between...
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