Article
Maximum, minimum, and optimal mutation rates in dynamic environments.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Dec 2009
Ancliff Mark, Park Jeong-Man
Abstract excerpt
We analyze the dynamics of the parallel mutation-selection quasispecies model with a changing environment. For an environment with the sharp-peak fitness function in which the most fit sequence changes by k spin flips every period T , we find analytical expressions for the minimum and maximum mutation rates for which a quasispecies can survive, valid in the limit of large sequence size. We find an asymptotic...
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