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Article

Linkage of angiotensin I-converting enzyme gene insertion/deletion polymorphism to the progression of human prostate cancer.

The Journal of pathology - 1 Mar 2004

Medeiros Rui, Vasconcelos André, Costa Sandra, Pinto Daniela, Lobo Francisco, Morais Antonio, Oliveira Jorge, Lopes Carlos

Abstract excerpt

Angiotensin-converting enzyme (ACE) degrades vasodilator kinins and generates angiotensin II (Ang II). It has been reported that ACE is synthesized by the prostate and that the AT-1 receptor subtype is the predominant prostatic Ang II receptor. A polymorphism in the human ACE gene has been described and the highest levels of circulating and tissue ACE activity are found in carriers of the DD genotype. In the...

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Identifiers

PMID: 14991898
DOI: 10.1002/path.1529

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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