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Angiotensin-converting enzyme insertion/deletion polymorphism and the risk of prostate cancer in the Han population of China.

Medical oncology (Northwood, London, England) - 1 Sept 2012

Wang Xiao, Wang Shuai, Lin Yi-wei, Wu Jian, Chen Hong, Mao Ye-qing, Zheng Xiang-yi, Zhou Cheng, Xie Li-ping

Abstract excerpt

As a main effector in the renin-angiotensin system, the angiotensin II plays a critical role in cell proliferation and angiogenesis. The change between angiotensin II and its precursor is conducted by the angiotensin-converting enzyme. The association between angiotensin-converting enzyme insertion/deletion polymorphism and the activity of angiotensin-converting enzyme was testified. Furthermore, previous...

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PMID: 21874567
DOI: 10.1007/s12032-011-0051-5

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