Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease.

Annals of neurology - 1 Mar 2004

Elbaz Alexis, Levecque Clotilde, Clavel Jacqueline, Vidal Jean-Sébastien, Richard Florence, Amouyel Philippe, Alpérovitch Annick, Chartier-Harlin Marie-Christine, Tzourio Christophe

Abstract excerpt

We performed a case-control study of Parkinson's disease (PD) in a population characterized by a high prevalence of pesticide exposure and studied the joint effect of pesticide exposure and CYP2D6. Although they are based on a small group of subjects with the joint exposure, our findings are consistent with a gene-environment interaction disease model according to which (1) pesticides have a modest effect in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Environmental Exposure

Share to Occupational Exposure

Share to Parkinson Disease

Share to Pesticides

Share to Prevalence

Source

Identifiers

PMID: 14991823
DOI: 10.1002/ana.20051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease.PMID 14991823Read ↗

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease.Semantic proximity Read ↗

CYP450, genetics and Parkinson's disease: gene x environment interactions hold the key.Semantic proximity Read ↗

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.Semantic proximity Read ↗

Parkinson's disease and pesticides: A meta-analysis of disease connection and genetic alterations.Semantic proximity Read ↗

Further evidence for the association of CYP2D6*4 gene polymorphism with Parkinson’s disease: a case control studySemantic proximity Read ↗

Pesticides and Parkinson's disease.Semantic proximity Read ↗

Genetic and environmental risk factors for Parkinson's disease in a Chinese populationSemantic proximity Read ↗

Commentary: Pesticides and GBA1 pathogenic variants in Parkinson's disease: An emerging and potentially dangerous association.Semantic proximity Read ↗

P450 enzymes and Parkinson's disease: the story so far.Semantic proximity Read ↗

Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.Semantic proximity Read ↗

Absence of effect of seven functional mutations in the CYP2D6 gene in Parkinson's disease.Semantic proximity Read ↗

Gene-gene and gene-environment interaction on the risk of Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.