Article
Polymorphisms in the vitamin D receptor gene, ultraviolet radiation, and susceptibility to prostate cancer.
Environmental and molecular mutagenesis - 1 Jan 2004
Bodiwala Dhaval, Luscombe Christopher J, French Michael E, Liu Samson, Saxby Mark F, Jones Peter W, Fryer Anthony A, Strange Richard C
Abstract excerpt
Ultraviolet radiation (UVR) exposure may protect against prostate cancer development via a mechanism involving vitamin D. The vitamin D receptor (VDR) gene is therefore a candidate susceptibility factor for prostate cancer. This possibility has been previously investigated with conflicting results. We examined the association of VDR genotypes (variants at the CDX-2, Fok1, and Taq1 sites), haplotypes, and genotype...
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