Article
Positive association of the androgen receptor CAG repeat length polymorphism with the risk of prostate cancer.
Molecular medicine reports - 1 Aug 2016
Paz-Y-Miño César, Robles Paulo, Salazar Carolina, Leone Paola E, García-Cárdenas Jennyfer M, Naranjo Manuel, López-Cortés Andrés
Abstract excerpt
Prostate cancer (PC) is the most frequently diagnosed cancer in Ecuador (15.6%). The androgen receptor gene codes for a protein that has an androgen‑binding domain, DNA‑binding domain and N‑terminal domain, which contains two polymorphic trinucleotide repeats (CAG and GGC). The aim of the present study was to determine whether variations in the number of repetitions of CAG and GGC are associated with the...
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