Article
Differential expression of CD44 variant isoforms by cell lines and tissue specimens of transitional cell carcinomas.
Anticancer research - 1 Jan 2000
Chuang Cheng-Keng, Liao Shuen-Kuei
Abstract excerpt
BACKGROUND: Certain splice variants (CD44v) can promote the progressive and metastatic behavior of cancer. We tested whether different CD44v molecules were selectively expressed in transitional cell carcinomas based on the stage and grade. MATERIALS AND METHODS: A panel of 13 TCC cell lines with different degrees of differentiation and biological behavior were tested with monoclonal antibodies to CD44s, CD44v5,...
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