Article
Predominant expression of CD44 splice variant v10 in malignant and reactive human skin lymphocytes.
The Journal of investigative dermatology - 1 Sept 1998
Wagner S N, Wagner C, Reinhold U, Funk R, Zöller M, Goos M
Abstract excerpt
The remarkable functional diversity of the cell surface receptor CD44 may be due to expression of multiple variant isoforms generated by alternative splicing of variant exons. Functional and correlative data implicate a role of CD44 variant isoforms in adhesion dependent processes such as lymphocyte recirculation and tumor progression and metastasis. We have analyzed 25 primary cutaneous lymphomas and 35 reactive...
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