Predominant expression of CD44 splice variant v10 in malignant and reactive human skin lymphocytes.

doi:10.1046/j.1523-1747.1998.00302.x

Back to search

Article

Predominant expression of CD44 splice variant v10 in malignant and reactive human skin lymphocytes.

The Journal of investigative dermatology - 1 Sept 1998

Wagner S N, Wagner C, Reinhold U, Funk R, Zöller M, Goos M

Abstract excerpt

The remarkable functional diversity of the cell surface receptor CD44 may be due to expression of multiple variant isoforms generated by alternative splicing of variant exons. Functional and correlative data implicate a role of CD44 variant isoforms in adhesion dependent processes such as lymphoc...

Topics

Alternative Splicing
Antibody Formation
Disease Progression
Exons
Genetic Variation
Humans
Hyaluronan Receptors
Lymphatic Metastasis
Lymphocytes
Lymphoma
Skin Diseases
Skin Neoplasms
Up-Regulation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.