Article
Hyperhomocysteinaemia in treated patients with Huntington's disease homocysteine in HD.
Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2004
Andrich Jürgen, Saft Carsten, Arz Anneliese, Schneider Birgit, Agelink Markus W, Kraus Peter H, Kuhn Wilfried, Müller Thomas
Abstract excerpt
Significantly increased plasma total homocysteine levels (t-Hcys) appeared in treated Huntington disease (HD) patients compared to controls and untreated HD subjects. Because the protein Huntingtin interacts with the homocysteine metabolism modulating enzyme cystathionine beta-synthase, we hypoth...
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