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Article

Effect of Homocysteine on Survival of Human Glial Cells

16 Oct 2015

Abstract excerpt

Several neurodegenerative conditions, such as Alzheimer's disease and Parkinson's disease, or vascular dementia and cognitive impairment, are associated with mild hyperhomocysteinemia. Hyperhomocysteinemia is defined as an increase of the homocysteine (Hcy) level beyond 10 microM. Although the adverse effect of Hcy on neurons is well documented, knowledge about the impact of this amino acid on glial cells is...

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PMID: 25804098
DOI: 10.33549/physiolres.932897

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