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Dissolved Oxygen Levels Alter Gene Expression and Antigen Profiles in Borrelia burgdorferi

21 Feb 2004

Abstract excerpt

The Lyme disease spirochete, Borrelia burgdorferi, encounters many environmental signals as it cycles between the arthropod vector and mammalian hosts, including temperature, pH, and other host factors. To test the possibility that dissolved oxygen modulates gene expression in B. burgdorferi, spirochetes were exposed to differential levels of dissolved oxygen, and distinct alterations were observed at both the...

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Identifiers

PMID: 14977964
DOI: 10.1128/iai.72.3.1580-1586.2004

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