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DNA microarray analysis of differential gene expression in <i>Borrelia burgdorferi</i> , the Lyme disease spirochete

5 Feb 2002

Abstract excerpt

DNA microarrays were used to survey the adaptive genetic responses of Borrelia burgdorferi (Bb) B31, the Lyme disease spirochete, when grown under conditions analogous to those found in unfed ticks (UTs), fed ticks (FTs), or during mammalian host adaptation (Bb in dialysis membrane chambers implanted in rats). Microarrays contained 95.4% of the predicted B31 genes, 150 (8.6%) of which were differentially...

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PMID: 11830671
DOI: 10.1073/pnas.032667699

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