Article
Regulatory role of microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase in a tobacco mutant that overproduces sterols.
Biochemical and biophysical research communications - 31 Jul 1992
Gondet L, Weber T, Maillot-Vernier P, Benveniste P, Bach T J
Abstract excerpt
In a tobacco mutant callus, containing up to tenfold more sterols than the wild-type genotype, HMG-CoA reductase activity is increased by a factor of approximately three, as is the case in mutant seedlings and plants. The rate of HMG-CoA synthesis from acetyl-CoA by the coupled enzyme system acetoacetyl-CoA thiolase/HMG-CoA synthase, as well as its conversion to acetyl-CoA plus acetoacetate by action of HMG-CoA...
Topics
- Cell Membrane
- Genotype
- Homeostasis
- Hydroxymethylglutaryl CoA Reductases
- Microsomes
- Mutation
- Plants, Toxic
- Sterols
- Nicotiana