Article
Analysis of distributions of amino acids in the primary structure of apoptosis regulator Bcl-2 family according to the random mechanism.
Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) - 1 Dec 2002
Wu Guang, Yan Shaomin
Abstract excerpt
It is no long a question whether the process of evolution is affected by chance, but is to what extent. The random analysis can throw light on the underlying reasoning for the primary structure of proteins. The study on the Bcl-2 family shows that the rank per amino acid increases 93% in bovine than in chicken and rat, which indicates that the effect of chance has more impact on the evolutionary process of...
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