Article
A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly.
Journal of lipid research - 1 May 2004
Curb J D, Abbott R D, Rodriguez B L, Masaki K, Chen R, Sharp D S, Tall A R
Abstract excerpt
High density lipoprotein cholesterol (HDL-C) levels are inversely associated with the incidence of coronary heart disease (CHD) in middle-aged individuals; in the elderly, the association is less clear. Genetic factors, including variations in the cholesteryl ester transfer protein (CETP) gene, play a role in determining HDL-C levels. Controversy remains about whether CETP deficiency and the resultant rise in...
Topics
- Age Factors
- Aged
- Aged, 80 and over
- Asian
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol Esters
- Cholesterol, HDL
- Coronary Disease
- Genetic Predisposition to Disease
- Glycoproteins
- Humans
- Longitudinal Studies