Article
Development and cross-validation of sequencing-based assays for genotyping common polymorphisms of the CXCL5 gene.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2006
Zineh Issam, Welder Gregory J, Langaee Taimour Y
Abstract excerpt
BACKGROUND: Epithelial neutrophil activating peptide (ENA-78) is encoded by the polymorphic CXCL5 gene and is a recruiter and activator of neutrophils. Furthermore, ENA-78 may be involved in pathological inflammatory processes and variable drug responses. METHODS: To facilitate future disease-gene and pharmacogenetic investigation of ENA-78, we developed and cross-validated medium- to high-throughput genotyping...
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