Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT

1 Feb 2004

Abstract excerpt

BACKGROUND: Cholangiocytes perform an essential role in important pathophysiologic functions in the liver. Establishment of a human cholangiocyte line facilitates advances in cholangiocyte research and clinical applications for cell therapies. Here, we describe the immortalization of human cholangiocytes using serial transfection of simian virus 40 large T (SV40T) followed by human telomerase reverse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Liver physiology and pathology
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14966424
DOI: 10.1097/01.tp.0000110292.73873.25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERTPMID 14966424Read ↗

ESTABLISHMENT OF AN IMMORTALIZED HUMAN-LIVER ENDOTHELIAL CELL LINE WITH SV40T AND hTERTSemantic proximity Read ↗

Establishment and characterization of a novel hilar cholangiocarcinoma cell line, CBC3T-1Semantic proximity Read ↗

Development of a cytokine-producing immortalized murine Kupffer cell line.Semantic proximity Read ↗

Development and characterization of human-induced pluripotent stem cell-derived cholangiocytesSemantic proximity Read ↗

Establishment and characterization of a simian virus 40-immortalized rat pancreatic stellate cell line.Semantic proximity Read ↗

Generation of functional ciliated cholangiocytes from human pluripotent stem cellsSemantic proximity Read ↗

Generation of functional ciliated cholangiocytes from human pluripotent stem cellsSemantic proximity Read ↗

Expression of transforming growth factor β1 promotes cholangiocarcinoma development and progressionSemantic proximity Read ↗

Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytesSemantic proximity Read ↗

Cholangiocarcinomas can originate from hepatocytes in miceSemantic proximity Read ↗

Transplantation of Conditionally Immortalized Hepatocytes to Treat Hepatic EncephalopathySemantic proximity Read ↗

Human placenta mesenchymal stem cell-derived exosomes delay H2O2-induced aging in mouse cholangioidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.