Article

Generation of functional ciliated cholangiocytes from human pluripotent stem cells

2021-03-23

Abstract excerpt

The derivation of mature functional cholangiocytes from human pluripotent stem cells (hPSCs) would provide a model for studying the pathogenesis of cholangiopathies and for developing novel therapies to treat them. Current differentiation protocols are not efficient and give rise to cholangiocytes that are not fully mature, limiting their therapeutic applications. Here, we describe a new strategy to generate funct...

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Literature Corpus work: 5ba1de2a-689c-5602-9bfb-cf1deab4934e
DOI: 10.1101/2021.03.23.436530

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