Article
Skin immune responses to peptide and protein antigen are TLR4 independent.
Cellular immunology - 1 Dec 2003
Kahlon Roopjeet, Dutz Jan P
Abstract excerpt
Little is known about the innate immune mechanisms regulating adaptive immune responses elicited through the skin. Tissue injury is postulated to liberate Toll like receptor 4 (TLR4) ligands. In this study, we determined whether TLR4 signaling modulates the response to epidermal injury induced by tape stripping (TS) and whether it alters humoral and cellular immune responses generated through epicutaneous...
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