Article
Overlapping mechanisms function to establish transcriptional quiescence in the embryonic Drosophila germline.
Development (Cambridge, England) - 1 Mar 2004
Deshpande Girish, Calhoun Gretchen, Schedl Paul
Abstract excerpt
In Drosophila melanogaster, the germline precursor cells, i.e. pole cells, are formed at the posterior of the embryo. As observed for newly formed germ cells in many other eukaryotes, the pole cells are distinguished from the soma by their transcriptional quiescence. To learn more about the mechanisms involved in establishing quiescence, we ectopically expressed a potent transcriptional activator, Bicoid (Bcd),...
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