Article
A mutational study of the ArcA-P binding sequences in the aldA promoter of Escherichia coli.
Molecular & general genetics : MGG - 1 Feb 1999
Pellicer M T, Lynch A S, De Wulf P, Boyd D, Aguilar J, Lin E C
Abstract excerpt
The aldA gene (encoding aldehyde dehydrogenase) of Escherichia coli is anaerobically repressed by ArcA-P, the phosphorylated response regulator of the ArcB/A two-component signal transduction system. The promoter region of aldA contains two 10-bp sequences (5'-TGTTAATTAA-3') that perfectly match the proposed ArcA-P binding consensus (5'-[A/T]GTTAATTA[A/T]-3'). One consensus sequence is on the coding strand (-13...
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