Article
KCNJ11 polymorphisms and sudden cardiac death in patients with acute myocardial infarction.
Journal of molecular and cellular cardiology - 1 Feb 2004
Jeron A, Hengstenberg C, Holmer S, Wollnik B, Riegger G A J, Schunkert H, Erdmann J
Abstract excerpt
PURPOSE: Patients with an acute myocardial infarction (AMI) are of high risk to develop ischemia-induced ventricular arrhythmias, leading to sudden cardiac death (SCD) in about one third of all AMI patients. The individual susceptibility to ischemia-induced arrhythmias may be modified by polymorphisms in genes encoding ion channels. The cardiac ATP-dependent potassium channel (K(ATP)) current is generated by ion...
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