Article
FAMMM syndrome: pathogenesis and management.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] - 1 Feb 2004
Czajkowski Rafał, Placek Waldemar, Drewa Gerard, Czajkowska Aldona, Uchańska Grazyna
Abstract excerpt
Familial atypical multiple mole melanoma (FAMMM) syndrome is an autosomal dominant disorder with variable incomplete penetrance of the clinical phenotypes. Pathogenesis of this syndrome has not been fully investigated. Across multiple studies, germline mutations in the INK4a antioncogene encoding p16 protein were found on average in approximately 40% of the FAMMM syndrome. Patients with the FAMMM syndrome are...
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