Article
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.
Antimicrobial agents and chemotherapy - 1 Oct 1996
Sanglard D, Ischer F, Monod M, Bille J
Abstract excerpt
Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal agent fluconazole after prolonged treatment with this compound. Most of the C. albicans isolates resistant to fluconazole fail to accumulate this antifungal agent, and t...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- ATP-Binding Cassette Transporters
- Antifungal Agents
- Antimetabolites
- Azoles
- Candida albicans
- Culture Media
- Drug Resistance, Microbial
- Genes, Fungal
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Transformation, Genetic