Article
Integrating gene expression and phenotypic information to analyze Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Ray Monika, Zhang Weixiong
Abstract excerpt
The assessment of the relationship between gene expression profiling, clinical and histopathological phenotypes would be better suited to understanding Alzheimer's disease (AD) pathogenesis. We developed a multiple linear regression (MLR) method to simultaneously model three variables - Mini-Mental Status Examination (MMSE) score, neurofibrillary tangles (NFT) score and gene expression profile - to identify...
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