Article
Association of angiotensin converting enzyme gene polymorphism with tachycardia cardiomyopathy.
International journal of molecular medicine - 1 Mar 2004
Deshmukh Pramod M, Krishnamani Rajan, Romanyshyn Mary, Johnson Andrew K, Noti John D
Abstract excerpt
Despite incessant tachycardia, not all patients develop tachycardia-mediated cardiomyopathy. The cardiac renin-angiotensin system may be involved in cardiac remodelling and fibrosis. The level of angiotension-converting enzyme (ACE) in the serum is associated with a 287 bp insertion (I)/deletion (D) polymorphism in intron 16 of the ACE gene. The DD genotype is associated with increased serum ACE levels and a...
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