Article
Alternative splicing in intracellular loop connecting domains II and III of the alpha 1 subunit of Cav1.2 Ca2+ channels predicts two-domain polypeptides with unique C-terminal tails.
The Journal of biological chemistry - 12 Jan 2001
Wielowieyski P A, Wigle J T, Salih M, Hum P, Tuana B S
Abstract excerpt
Novel splice variants of the alpha(1) subunit of the Ca(v)1.2 voltage-gated Ca(2+) channel were identified that predicted two truncated forms of the alpha(1) subunit comprising domains I and II generated by alternative splicing in the intracellular loop region linking domains II and III. In rabbit heart splice variant 1 (RH-1), exon 19 was deleted, which resulted in a reading frameshift of exon 20 with a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
